Michigan State University
MSU Food Science and Human Nutrition

Faculty

Kate Claycombe, Assistant Professor

Kate Claycombe

 

Postdoctoral Fellow, Nutritional Immunology, Tufts University
Ph.D., Nutritional Science, University of Tennessee at Knoxville
M.S., Biology, East Tennessee State University

302A G.M. Trout FSHN Building
Michigan State University
East Lansing, MI 48824-1224
Phone: (517) 355-8474, Ext. 133
Lab: (517) 355-8474, Ext. 159
Fax: (517) 353-8963
E-mail: claycom3@msu.edu


Research Interests: 

Obesity-Associate Immune Dysfunction and Inflammation: Role of Anti-Inflammatory Nutrients.

Instructional Activities:

Advanced Human Nutrition: Vitamins and Minerals, Nutritional Biochemistry, Nutritional Immunology in Obesity.

Recent Publications:

Kusai Aziz, Kevin Berger, Kate J. Claycombe, Hongbao Ma, Ruiping Huang, Roshan Patel, and George S. Abela, Non-invasive detection and localization of vulnerable plaque and arterial thrombosis using CTA/PET, Accepted, Circulation, Feb. 2008.

Claycombe, K., King, L., and Fraker, P., A role for leptin in sustaining lymphopoiesis and myelopoiesis. PNAS, in press, January 2008.

Ock Kyoung Chun, Sang Jin Chung, Kate J. Claycombe, and Won O. Song, Serum C-reactive protein concentrations are inversely associated with dietary flavonoid intake in U.S. adults, Accepted, J. Nutr, January 2008.

Zhou, H.R., Kim, E.K., Kim, H., and Claycombe, K.J., Obesity-associated mouse adipose stem cell secretion of monocyte chemotactic protein-1 (MCP-1). Am J Physiol Endocrinol Metab. Aug 28, 2007.

Harkins JM, Moustaid-Moussa N, Chung YJ, Penner KM, Pestka JJ, North CM and Claycombe KJ. "Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice." J. Nutr. 134(10):2673-7, 2004.

Wu D, Marko M, Claycombe KJ, Paulson KE and Meydani SN. "Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated throgh upregulation of NF- kappa B activity." J. Biol. Chem. 278(13):10983-92, 2003.

Claycombe KJ, Wu D, Nikolova-Karakashian M, Palmer H, Beharka A and Paulson KE. "Meydani SN, Ceramide me diates age-associated increase in macrophage cyclooxygenase-2 expression." J. Biol. Chem. 277(34):30784-91, 2002.

Heo YR, Claycombe KJ, Jones BH, Wright P, Truett GE, Zemel M, Banz W, Maher M and Moustaid-Moussa N. "Effects of fatty (fa) allele and high-fat diet on adipose tissue leptin and lipid metabolism." Horm. Metab. Res. 34(11-12):686-690, 2002.

Kim S, Whelan J, Claycombe KJ, Reath DB and Moustaid-Moussa N. "Angiotensin II increases leptin secretion by 3T3-L1 and human adipocytes via a prostaglandin-independent mechanism." J. Nutr. 132(6):1135-40, 2002.

Koga T, Claycombe KJ and Meydani M. "Homocysteine increases monocyte and T-cell adhesion to human aortic endothelial cells." Atherosclerosis. 161(2):365-74, 2002.

Claycombe KJ, Wang Y, Jones BH, Kim S, Wilkison WO, Zemel MB, Chun J and Moustaid-Moussa N. "Transcriptional regulation of the adipocyte fatty acid synthase gene by agouti: interaction with insulin." Physiol. Genomics. 3:157-62, 2000.

Claycombe KJ, Xue BZ, Mynatt RL, Zemel MB and Moustaid-Moussa N. "Regulation of leptin by agouti." Physiol. Genomics. 2:101-5, 2000.

Moussa NM and Claycombe KJ. "The yellow mouse obesity syndrome and mechanisms of agouti-induced obesity." Obes. Res. 7:506-14, 1999.

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